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MSC-131 - Design and Deploy AirDefense Solutions - Dump Information

Vendor : Motorola
Exam Code : MSC-131
Exam Name : Design and Deploy AirDefense Solutions
Questions and Answers : 103 Q & A
Updated On : November 17, 2017
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MSC-131 Questions and Answers


Answer: A


QUESTION: 98

When configuring AP Radio Settings from ADSP, which of the following functions would help you to determine if Hidden Nodes are causing an inordinate number of collisions in your WLAN?

  1. DTIM Period
  2. Beacon Period
  3. RTS Threshold
  4. Fragmentation Threshold

Answer: C


QUESTION: 99

The ADSP CLI Configuration profile exhibit at the bottom is showing the configuration for which vendor?

  1. Cisco
  2. Brocade
  3. Motorola
  4. Extreme Networks

Answer: A


QUESTION: 100

Which of the following describes ways in which you can sanction WLAN devices (select TWO)?

  1. File import
  2. DHCP option
  3. Static IP address
  4. Manual selection
  5. RADIUS authentication

Answer: A, D


QUESTION: 101

The Alarm detail shown in Exhibit 7.2.07, identifies a Rogue AP that has infiltrated your WAN. What mitigation procedures are available to you in this circumstance (select THREE)?

  1. Enable Honeypot
  2. Locate and Remove
  3. Wireless Termination
  4. Mask Rogue Beacons
  5. White Noise Blankets
  6. Wired Port Suppression

QUESTION: 102

Does the ADSP fit well into IT Service Management (ITSM) process frameworks, like IT1L (IT Infrastructure Library) and ISO/IEC 20000?

  1. Yes, because most of the modules can be mapped to each of the process areas, like Configuration Management, Incident Management, Change Management, Service Level Management.
  2. Yes, but it only fits in the ITIL processes and not in the ISO/IEC 20000 processes.
  3. Yes, but it only fits in the ISO/IEC 20000 processes and not in the UIL processes.
  4. Yes, because only one module can be mapped to Incident Management.

Answer: A


QUESTION: 103

AirDefense supports the visualization of wired devices behind wireless Access Points using which one of the Analysis Tools?

  1. Advanced Forensics
  2. Spectrum Analysis
  3. Scope Forensics
  4. LiveRF
  5. Live View
  6. Location Tracking

Answer: E


Motorola MSC-131 Exam (Design and Deploy AirDefense Solutions) Detailed Information

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School district connects directly to first responders with an instant line of communication. MOTOTRBO and SchoolSAFE open the channel to exceptional interoperability.
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Free Grant Assistance for Schools
Free Grant Assistance for Schools
Motorola partners with EducationGrantsHelp to provide schools with free grant research, application assistance and more for radio systems and SchoolSAFE.
Higher Ed: Campus Security
Increase Contextual Awareness, Accelerate Responsiveness, Improve Decision-Making and Make Your City Safer.
VDC Research: Benefits of Selecting Two-Way Radios Over Cell Phones
There is no one-size fits all when it comes to communications solutions. Learn about the role of the two-way radio in your everyday operations.
Help Your Students and Staff Stay Safer, Together
Provide seamless communications for your school personnel anywhere they go with unified voice and data.
Find the Right Communication Solution for Your Needs
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Explore your options with the MOTOTRBO selection tool
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Over 900 educators weighed in on the evolving state of school communications. See how your school compares nationwide and learn about the top trends in school safety.
We build customers' technical competencies to solve their business needs and maximize return on their MSI investments.
Choosing Motorola Solutions is only the beginning.
Next: Get trained on Motorola Solutions’ latest innovations and improve your proficiency with our expanding training portfolio!
With versatile training solutions and best practices from our expert instructors and designers, you can increase the return on your technology investment throughout the product and system lifecycle.
Motorola Solutions Learning provides your organization a one-stop shop, end-to-end training service: from needs analysis and consultancy to course development, customization, delivery, and logistics. Let Motorola Solutions Learning work with your team to ensure that your organization configures, operates and maintains your products and systems to effectively and efficiently meet your specific needs.
Technical Training Courses:
Product Technical Training Courses
Get trained on Motorola Solutions' latest innovations and improve your proficiency with our expanding training portfolio. Browse courses and view curriculum roadmaps specific to your Radio Solution needs.
We offer a wide range of training courses to help you get the most from your training system.
Our specialized curriculum roadmaps are designed for your role. Whether you are an administrator, technician or user, we make sure you are equipped with foundational and advances skills. Choose your product and/or system training from the list below:
Courses
Foundational
Base Stations
Consoles
ASTRO® 25 IV&D Systems
Dimetra System (region specific)
MOTOTRBO
TETRA (region specific)
Professional Commercial Radio
Subscribers
Public Safety LTE
ETA offers both proprietary and non-proprietary certifications for Motorola and Channel Partner technicians. Motorola Solutions recommends that all technicians take the basic electronics Associate Certified Electronics Technician (CETa) - designated as CESa in Canada - exam prior to obtaining any of these certifications.
Many technicians are also choosing to achieve the full Journeyman-level CET (designated as CES in Canada) status by taking either the Wireless Communications (WCM) or the TRN Wireless Communications Technician (TRN) certification. Others have gone on to attain Senior Status (CETsr) or even Master Status (CETma) level CET certification.
Please note that all examinees must register for training through Motorola Solutions for the Hands-On portion of the exams. ETA does not provide training. The written portion can be taken at one of ETA's many test sites around the world.
ETA has provided this page to help answer some of the most commonly asked questions about Motorola certification programs, as well as to help identify Motorola-specific resources for examination testing.
Resources
The Associate CET Study Guide
FCC GROL Plus Study Guide
FCC GROL Plus Study Guide w/ CD
National Electrical Code
Motorola R56 Manual
Motorola Parts Department -
(800) 422-4210
Manual part number - 68P81089E50-8
Limited Energy and Comm Systems
Motorola Solutions Training Home
R56 Certification Preparation Guide
Retired Motorola Certifications
The Radio Network Administrator (RNA)
Radio Systems Technician (RST)
CENTRACOM Gold Elite Console System Technician (CCT)
MCC5500 Dispatch Console Technician (MCC55)
CENTRACOM Gold Elite System Console Tech (Centracom)
Quantar Repeater Site Tech (QRST)
Wireless Broadband Value Adder Reseller Mobile (Wibb VVAR)
Fixed and Mobile Motorola Wireless Field Engineer (MWFE)
Motorola Wireless Systems Engineer (MWSE)
Motorola Wireless Systems Administrator (MWSA)
Motorola Wireless Systems Technician (MWST)
ASTRO® 25 Series Registration
Registration is now being taken through the Motorola LMS system. You may register for one of these sessions at http://learning.motorolasolutions.com. Motorola Technicians who take the ASTRO® 25 Series as a Stand-Alone are not yet required to take the Associate CET exam. The ASTRO® 25 series cannot be earned at a Journeyman level due to the RNA and Console certification retirements.
Motorola ASTRO® 25 Series Certifications
M Core Technician (MCT 7.x)
Motorola employees and affiliates are eligible for the required ASTRO® 25 IV&D M CORE WORKSHOP course.
Exam/Practical Hands-On are online only. Exams are not available at the course training site.
Passing score is 80% and there is a three hour time limit.
If the exam is not passed by the second attempt, then the individual must attend another Motorola ASTRO® 25 IV&D M CORE WORKSHOP class before attempting the exam again.
Certification is valid for four years, and not eligible for maintenance.
The current M Core certification exam must be retaken at or after expiration (90 day grace).
If the recertification exam is not passed by the first attempt, then the individual must attend another Motorola class to take the exam again, which will be the free retake.
Does not count towards Master CET status.
Motorola Technicians who take the ASTRO® 25 Series as a Stand-Alone are not yet required to take the Associate CET exam. Attendance of the corresponding ASTRO® 25 M Core training course is mandatory.
MCT Exam Info
Prior experience with an ASTRO® 25 7.x radio system is strongly recommended as a prerequisite to the certification. The most recent radio system update is the standard.
Price (Theory/Practical): $330
Type of Certification: Stand-Alone
Maintenance Required: No
Certification Term: 4 Yrs
Hands-On Required: Yes
Questions on Exam: 100
Passing Score: 80%
Time Allowed to Test: 3 hours
Competencies - What's covered?
Register for training
GTR 8000 Repeater Site Technician (GTT)
Motorola employees and affiliates are eligible for the required ASTRO® 25 IV&D GTR 8000 REPEATER SITE WORKSHOP course.
Exam/Practical Hands-On are online only. Exams are not available at the course training site.
Passing score is 80% and there is a three hour time limit.
If the exam is not passed by the second attempt, then the individual must attend another Motorola ASTRO® 25 IV&D GTR 8000 REPEATER SITE WORKSHOP class and take the exam again.
Certification is valid for four years, and not eligible for maintenance.
The current GTR 8000 Repeater Site certification exam must be retaken after expiration (90 day grace).
If the recertification exam is not passed by the first attempt, then the individual must attend another Motorola class and take the exam again, which will be the free retake.
Does not count towards Master CET status.
Motorola Technicians who take the ASTRO® 25 Series as a Stand-Alone are not yet required to take the Associate CET exam. Attendance of the corresponding ASTRO® 25 GTR 8000 Repeater Site training course is mandatory.
GTT Exam Info
Price (Theory/Practical): $330
Type of Certification: Stand-Alone
Maintenance Required: No
Certification Term: 4 Yrs
Hands-On Required: Yes
Questions on Exam: 65
Passing Score: 80%
Time Allowed to Test: 3 hours
Competencies - What's covered?
Register for training
Motorola Communication Site Certifications
Communication Site Installer (R56)
Motorola employees and affiliates only unless Motorola Solutions authorization given for attendance.
Must complete a Motorola Solutions COMMUNICATIONS SITE INSTALLATION PRACTICES WORKSHOP (R56) training course. Provide written evidence of having attended the instructor-led Motorola Solutions Site Installation Practices Workshop.
The NEW NST925 training course is offered mainly at the Motorola training facility in Schaumburg, IL. The class schedule can be accessed via your Motorola Online account.
Training course may be offered in the field (NEW RTW050) under special circumstances. Contact your local Motorola Account Representative and/or Customer Support Manager or ETA International.
Examination must be taken within a year of completing the required training course.
Can be taken as an ETA Stand-Alone or Journeyman Option (w/ Associate CET (CETa)) for the certified R56.
If the initial R56 exam is not passed (75%) by the second attempt, then the individual must attend another Motorola class and take the exam again.
R56 certification is valid for four years and not eligible for maintenance.
Recertification of R56 Certification
The training for R56 provided by Motorola Solutions has been updated along with the manual. R56 recertification procedures are outlined on page 2 of the COMMUNICATION SITE INSTALLER (R56) PREPARATION GUIDE. Completion of either the full NST925/RTW050 course as described above or the NEW R56 STANDARDS UPDATE 2016 COURSE = NST925-5 are required. The NST925-5 course can be found online or the one-day instructor led course is suggested.
Anyone that renewed their R56 certification during 2013-2015 will not be required to attend the updated class until their certification four year term is complete.
Anyone that renewed their R56 certification during the last two quarters of 2012 should schedule their NST925-5 one-day instructor led course and begin study for the new recertification exam.
Anyone who let their R56 certification expire (earned prior to March 2012) should consider the full NST925/RTW050 course. You will qualify for the recertification with the NST9525-5, but you may not be fully knowledgeable of all of the updated standards and practices. Your R56 will recertify, but the new date earned will take precedence. You will have a lapse period between expiration and re-certification.
If you hold a Standalone R56 and later complete the Associate CET (CETa), then you are eligible to upgrade to a Journeyman CET! To apply for the Journeyman CET, you must have two or more years of combined work and electronics training. To upgrade, please fill out the Journeyman CET upgrade form. Journeyman upgrades are $50.
Additional Information
R56 Certification Preparation Guide
R56 Exam Info
Price (Theory/Practical): $100
Type of Certification: Journeyman or
Stand-Alone
Maintenance Required: No
Certification Term: 4 Yrs
Hands-On Required: Yes
Questions on Exam: 112
Passing Score: 75%
Time Allowed to Test: 2 hours
Competencies - What's covered?
Register for training
Communication Site Installation Inspector (CSII)
Only Motorola employees and affiliates invited by Motorola authorization are eligible.
Must complete a Motorola Solutions Communications Site Installation Practice Workshop Inspector (R56 with auditor details) training course.
Examination must be taken within a year of completing the required training course.
If the initial CSII exam is not passed (75%) by the second attempt, then the individual must attend another Motorola class and take the exam again.
Must have attained the Associate CET (CETa) certification as a prerequisite. The CSII will not be issued without the Associate CET to attain the Journeyman Option.
Certification is valid for four years and not eligible for the maintenance. Course/Exam must be retaken at expiration.
Additional CSII (R56 Auditor) information will be updated and available soon.
Recertification of CSII Certification
The training for CSII provided by Motorola Solutions is currently being updated. Until more detailed CSII information is available, please review the updated R56 information.
R56 recertification procedures are outlined on page 2 of the COMMUNICATION SITE INSTALLER (R56) PREPARATION GUIDE. Completion of either the full NST925/RTW050 course as described above or the NEW R56 STANDARDS UPDATE 2016 COURSE = NST925-5 are required. The NST925-5 course can be found online or the one-day instructor led course is suggested.
Anyone that renewed their CSII certification during 2013-2015 will not be required to attend the updated class until their certification four year term is complete.
Anyone that renewed their CSII certification during the last two quarters of 2012 should schedule their NST925-5 one-day instructor led course and begin study for the new recertification exam along with contacting Schaumburg concerning CSII details.
Anyone who let their CSII certification expire (earned prior to March 2012) should consider the full NST925/RTW050 course. You may qualify for the recertification with the NST9525-5, but you may not be fully knowledgeable of all of the updated standards and practices. Your CSII will recertify, but the new date earned will take precedence. You will have a lapse period between expiration and re-certification. Please contact Schaumburg for more details.
CSII Exam Info
Price (Theory/Practical): $100
Type of Certification: Journeyman
Maintenance Required: No
Certification Term: 4 Yrs
Hands-On Required: Yes
Questions on Exam: 120
Passing Score: 75%
Time Allowed to Test: 2 hours
Competencies - What's covered?
Register for training
Other Motorola Certifications
ETA also offers the following tests for Motorola technicians, Motorola Solutions representatives, and those with an Associate CET (CETa) attempting to achieve ETA International Journeyman Certified Electronics Technician (CET) status. Tests can be used as the journeyman portion of the knowledge test.
Antenna Systems Analysis (ASA)
Motorola employees and affiliates only unless specifically invited.
Must complete the MOTOROLA SOLUTIONS ANTENNA SYSTEM ANALYSIS USING A FREQUENCY DOMAIN REFLECTOMETER training course.
Must have attained the Associate CET (CETa) plus the Wireless Communications (WCM) or TRN Wireless Communications Technician (TRN) certifications. The technician must be Journeyman-certified or become Journeyman certified before the ASA certification can be issued.
This Frequency Domain Reflectometer (FDR) certification includes a hands-on verification of modern FDR equipment usage and a written exam that must be passed with a score of 75%.
Examination must be taken within a year of completing the required training course.
If the exam is not passed by the second attempt, then the individual must attend another Motorola class and take the exam again.
Must be renewed through the Maintenance program.
ASA Exam Info
The PREREQUISITES for the ASA are the Associate CET (CETa) and Wireless Communications (WCM) or TRN Wireless Communications Technician (TRN) certifications.
Price (Theory/Practical): $100
Type of Certification: Journeyman
Maintenance Required: Yes
Certification Term: 4 Yrs
Hands-On Required: Yes
Questions on Exam: 100
Passing Score: 75%
Time Allowed to Test: 2 hours
Competencies - What's covered?
Register for training
RF Signal Investigation Techniques (RFSIT)
Motorola employees only unless specifically invited.
Motorola technologists and engineers who have completed the the MOTOROLA RF SIGNAL INVESTIGATION TECHNIQUES USING A SPECTRUM ANALYZER training course are eligible to sit for the exam.
This spectrum analysis certification includes a hands-on verification of modern spectrum analyzer equipment usage and a written exam that must be passed with a score of 75% or higher.
Journeyman Option only. The RFSIT will not be issued without having attained the Associate CET (CETa) certification.
Examination must be taken within a year of completing the required training course.
If the exam is not passed by the second attempt, then the individual must attend another Motorola class and take the exam again.
Must be maintained through the Maintenance program.
RFSIT Exam Info
Price (Theory/Practical): $100
Type of Certification: Journeyman
Maintenance Required: Yes
Certification Term: 4 Yrs
Hands-On Required: Yes
Questions on Exam: 75
Passing Score: 75%
Time Allowed to Test: 2 hours
Register for training
T1 Link Verification (LV)
Must complete the T1 Link Verification training course.
Examination must be taken within a year of taking the required training course.
If the exam is not passed by the second attempt, then the individual must attend another Motorola class and take the exam again.
Journeyman Option only. The T1 will not be issued without having attained the Associate CET (CETa) certification.
Must be maintained through the Maintenance program.
LV Exam Info
Price (Theory/Practical): $100
Type of Certification: Journeyman
Maintenance Required: Yes
Certification Term: 4 Yrs
Hands-On Required: Yes
Questions on Exam: 75
Passing Score: 75%
Time Allowed to Test: 2 hours
Register for training
GTR 8000 P25 RF Site Performance Verification (GSPV / GTR-SPV)
Motorola employees and affiliates only unless invited and Motorola authorization given.
Must have prior experience with ASTRO25 GTR 8000 P25 base radio sites and equipment.
Applicable two-day GTR 8000 P25 RF Site Performance Verification procedure training course is available but not mandatory. Contact your local Motorola Account Representative and/or Customer Support Manager.
Is available as an ETA Journeyman or Stand-Alone certification; not to be confused with the Stand-Alone type of GTR 8000 hardware platform.
The exam must authorized by Motorola Solutions.

Motorola MSC-131

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    Quantification of energetic pharmaceutical ingredient and impurities in sildenafil citrate received from the internet Ther Adv Drug Saf. 2014 Oct; 5(5): a hundred and eighty–189.
    PMCID: PMC4212438
    Michael A. Veronin, Texas A&M school health Science middle Rangel school of Pharmacy - Pharmaceutical Sciences, MSC 131 1010 West Avenue B, Kingsville, TX 78363-8202, us of a;
    summary historical past:
    The accessibility of prescription medicine produced backyard of the united states, most mainly sildenafil citrate (innovator product, Viagra®), has been made a whole lot easier with the aid of the internet. Of most reliable subject to clinicians and policymakers is product first-class and affected person protection. the USA meals and Drug Administration (FDA) has issued warnings to knowledge patrons that the protection of medication purchased from the internet can't be assured, and can present a fitness possibility to patrons from substandard items.
    aim:
    The objective of this study MSC-131 was to verify no matter if ordinary sildenafil citrate pills from international markets received by the use of the information superhighway are such as the united states innovator product related to major elements of pharmaceutical high-quality: efficiency, accuracy of labeling, and presence and stage of impurities. this could support establish elements of drug first-rate that may additionally have an effect on public health dangers.
    methods:
    a complete of 15 sildenafil citrate capsules were received for pharmaceutical analysis: 14 regularly occurring samples from overseas web pharmacy web sites and the us innovator product. in accordance with US Pharmacopeial guidelines, tablet samples have been established using excessive-performance liquid chromatography for efficiency of active pharmaceutical ingredient (API) and levels of impurities (impurities A, B, C, and D). Impurity levels were compared with overseas conference on Harmonisation (ICH) limits.
    results:
    among the 15 samples, four samples possessed greater impurity B levels than the ICH qualification threshold, eight samples possessed better impurity C tiers than the ICH qualification threshold, and 4 samples possessed more than 1% impurity amount of highest daily dose (MDD). For API, 6 of the samples didn't fall within the 5% assay restrict.
    Conclusions:
    first-rate assurance tests are often used to become aware of system defects of drug products all over the manufacturing and/or storage manner. outcomes indicate that manufacturing requisites for sildenafil citrate normal drug items compared with the U.S. innovator product are not equivalent concerning efficiency and stages of impurities. These findings have implications for protection and effectiveness that should still be addressed by means of clinicians to defend consumers who choose to buy sildenafil citrate and international-manufactured drugs, in universal, via the cyber web.
    keywords: drug importation, drug first-class, drug defense, cyber web pharmacy, first-class assurance testing, sildenafil citrate, Viagra®
    Introduction
    in line with the countrywide affiliation of Boards of Pharmacy (NABP), ninety seven% of the over 10,000 internet drug ‘shops’ that NABP has assessed perhaps illegitimate or illegal, and out of compliance with pharmacy laws and observe requisites [National Association of Boards of Pharmacy, 2014]. Sildenafil (Viagra®) is a suitable-selling, in all probability the choicest-promoting, illicit drug bought on the web [BBC News, 2002]. definitely, the pharmaceutical company Pfizer, who first introduced Viagra to market in 1998, is setting up its personal web page to promote Viagra online, in what it says is an effort to curb the sale of counterfeit types of the drug [Isidore, 2013].
    Viagra turned into the first remedy for erectile dysfunction in an oral dosage form. originally, it was studied for remedy of hypertension and angina pectoris, but early scientific trials suggested that although it had little effect on angina, it changed into observed to induce penile erections. as a result, Pfizer made the resolution to market Viagra for erectile dysfunction [Ghofrani et al. 2006]. What followed became an immediate healthcare, if not absolute, company success. in accordance with reviews at the time: ‘inside two weeks, newspapers said physicians have been writing 15,000 to twenty,000 prescriptions a day for the remedy’ [Rodriguez, 1998]. within the week of eight may 1998, and 1 month after Viagra’s release, greater than 300,000 complete prescriptions have been written for Viagra within the US, and Pfizer stated that greater than US$400 million value of Viagra became bought in the first quarter [Keith, 2000].
    more currently, in line with the healthcare consulting firm IMS fitness, approximately eight million prescriptions for Viagra have been written in 2012, which interprets into total revenue of about US$2 billion. And of the ‘market share’ for prescription drugs for erectile dysfunction, which additionally contains Cialis, Levitra, and Staxyn [Drugs.com, 2014], Viagra has about forty five% of the market, simply ahead of Eli Lilly’s Cialis [Wilson, 2013].
    As an illustration of the recognition of online sildenafil, a web search using the search phrases ‘online sale Viagra’ resulted in over 1.5 million hits, directing the person to places of information superhighway pharmacies promoting familiar versions of this product [Lowe and Costabile, 2011]. email unsolicited mail for Viagra is so pervasive that Microsoft and Pfizer jointly filed a few court cases against pharmacy unsolicited mail rings operating websites that allegedly sell general Viagra. tens of millions of disruptive e-mail messages probably entice buyers to these URLs promoting illegal Viagra. according to some estimates, Viagra and other erectile dysfunction medicines or treatments may additionally account for as an awful lot as 1 / 4 of all spam [Information Week, 2005].
    an important key concern of cyber web drug importation, and of considerable problem to clinicians and healthcare policymakers, is affected person defense because of bad product fine. in response to the U.S. meals and Drug Administration, ‘FDA can't be certain the security and effectiveness of products that don't seem to be FDA-authorized and are available from unknown sources and foreign areas, or that might also no longer had been manufactured under proper circumstances. These unknowns put affected person’s health in danger in the event that they can't make certain of the products id, purity, and source. For these factors, FDA recommends handiest obtaining medicines from legal sources in the U.S.’ [US Food and Drug Administration, 2010]. a number of studies validate the assertion that medicine produced in many overseas countries don't meet equal standards of fine as within the US [US Food and Drug Administration, 2004; Qureshi and McGilveray, 1998; Westenberger et al. 2005; Veronin and Youan, 2004].
    In a previous look at, a excessive-efficiency liquid chromatography (HPLC) assay components became developed and validated for sildenafil citrate and its linked resources that could coexist in pills’ method [Daraghmeh et al. 2001]. These compounds involving sildenafil may be impurities or may additionally seem as degradation products and had been organized and identified as impurity A, impurity B, impurity C, and impurity D.
    The requirements for assessing safeguard of impurities in drug products can be found in the instructions from the international convention on Harmonisation of Technical necessities for Registration of pharmaceuticals for Human Use (ICH). established in 1990, the ICH is ‘unique in bringing collectively the regulatory authorities and pharmaceutical trade of Europe, Japan and the USA to discuss scientific and technical features of drug registration.’ [ICH, 2014].
    ICH has developed instructions for threshold of impurity amount in new drug items [ICH, 2006], which are presented in . Per ICH instructions, identification threshold is the restrict above which a degradation product should still be identified. Reporting threshold is the restrict above which the degradation product should be reported to regulatory bodies. Qualification is the procedure of buying and evaluating information which establishes the biological defense of someone impurity or a given degradation profile at a certain degree. TDI is the full each day intake of the drug. If the impurity is strangely toxic, lessen threshold values are appropriate. optimum each day dose (MDD) is the maximum quantity of drug administered per day.
    Thresholds for impurities in new drug products [ICH, 2006].
    This look at reports on the drug product variability of sildenafil. The purpose of this look at is to assess whether generic sildenafil tablets from international markets acquired via the cyber web are related with the U.S. innovator product with regard to foremost facets of pharmaceutical best: efficiency and accuracy of labeled quantity, and degree of impurities.
    at the moment, the innovator product for sildenafil (Viagra®, Pfizer) is blanketed by way of a US patent [Milford, 2011], yet is with ease purchasable to patrons in regular kind from the web. The highest advised daily dose of sildenafil citrate is one hundred mg [Drugs.com, 2014], and for this reason, this was the dosage strength chosen for evaluation in this examine.
    substances and methods sample acquisition
    Searches of the everywhere net have been carried out with the browser cyber web Explorer 7.0. The web sites for the information superhighway pharmacies had been discovered by using the advanced search options of Google (http://www.google.com.) The key phrases chosen for entry into the question box of the browser covered the hunt terms ‘common Viagra’, ‘usual sildenafil’, ‘on-line pharmacy’, and ‘information superhighway pharmacy’. All proprietary forms of sildenafil one hundred mg drugs had been recognized on the web sites for prospective procurement. Our viewpoint changed into that of a buyer searching for to buy these prescription drugs on-line or assessment expense shopping. If vital, drug items have been bought a second time from the same web site to validate examine findings of the preliminary pattern.
    all through January 2010 via July 2010, 15 sample plenty had been bought from the united states and international markets. the USA innovator product changed into acquired by means of prescription from Harrel’s Kingsville Pharmacy (Kingsville, TX, u . s .), and other samples from web pharmacy sites. A checklist of attributes turned into created for every specific drug product ().
    features of sildenafil pill samples.
    For analyses involving HPLC, the pure pharmaceutical grade chemical for sildenafil changed into received from Toronto analysis chemicals Inc. (Toronto, Ontario, Canada; Lot #5-KPA-93-1, Catalog #A617415). Impurity A was obtained from ChemPacific (Baltimore, MD; Lot #CHP-20-10232-207-6, Catalog #33854), impurity B was received from Equinox chemical substances (Albany, GA; Lot EQX-2009-D-030, Catalog #E-03-0316), impurity C become got from Specs (The Netherlands; Product identification #AP-312/40633649), impurity D become received from Sigma-Aldrich (St. Louis, MO; Lot #04710EH, Product #535524).
    instruction of solutions
    To prepare standard options of energetic pharmaceutical ingredient (API), 25 mg of sildenafil citrate become accurately weighed and dissolved in 50 ml of mobile part (500 µg/ml awareness), sonicated for 15 minutes and filtered through 0.forty five µm filter. extra dilutions have been carried out to gain sildenafil citrate inside a target awareness range of 5–500 µg/ml.
    To prepare typical answer of impurities, 1 mg every of impurities A, B, C, and D have been weighed and dissolved in a hundred ml of cellular section (10 µg/ml awareness), sonicated for quarter-hour, and filtered via a typical 0.45 µm filter. extra dilutions were carried out to gain impurities with in target concentration range of 5–one hundred µg/ml.
    HPLC evaluation
    prior to trying out, HPLC analytical device became calibrated in keeping with manufacturer’s necessities via licensed technicians. where applicable, the applicable USP guidelines have been utilized for trying out procedures [United States Pharmacopeial Convention, 2003].
    An HPLC methodology for sildenafil evaluation has been pronounced in the past by way of Daraghmeh and colleagues [Daraghmeh et al. 2001], and this analytical method become modified and employed in this look at.
    HPLC evaluation became carried out on a Waters 1525 Binary HPLC pump outfitted with an inline degasser AF, a Waters 2487 dual λ absorbance detector, and a Waters 717 plus autosampler. facts turned into analyzed the use of Waters Breeze application. Centrifugation turned into carried out by the Eppendorf Centrifuge 5430, and sonification become carried out with the Fisher Scientific Ultrasonic Cleaner FS20.
    Measurements have been made with a 20 µl injection extent at 30°C; the detector wavelength become set at 240 nm and the retention time turned into 6.four minutes. movements analyses had been performed isocratically on a Waters X Bridge C18, 5 µm column (250 mm × four.6 mm), eluted with a cellular part including acetonitrile/ammonium acetate buffer (50:50 v/v), pH 7.0, at a flow rate of 1.0 ml/min. Pure sildenafil (Sigma-Aldrich, St. Louis, MO) acetonitrile (Aldrich Laboratories, Milwaukee, WI), ammonium acetate buffer (Fisher Scientific, Rochester, big apple), water (Barnstead Nanopure ultrapure water purification equipment, Fisher Scientific, Rochester, new york), had been used to put together standard curves for each assay. Quantitation become completed through evaluation of height enviornment to a typical curve. All analyses were performed in triplicate and the error expressed as ordinary deviation.
    To prepare an answer of tablet samples of 1 mg/ml awareness, 10 drugs have been pulverized with mortar and pestle and parts equivalent to 100 mg sildenafil citrate were weighed and transferred into a hundred ml usual volumetric flasks. Upon addition of cell phase (100 ml), sonication, centrifugation (quarter-hour at 3000 rpm), 20 µl of the supernatant turned into injected into the chromatograph. This evaluation became used to calculate the regular impurity and regular API volume current in a dosage kind one particular person sample set. This components can get rid of the error led to by pill weight variation in decision of regular impurity and API portions.
    To quantify the impurity and API stages, the calibration curve components the usage of typical plots changed into used. For sildenafil, and impurities A, B, C, and D, linear curves were plotted the use of respective general compounds. As per ICH Q2R1 instructions for analytical process validation, the standard plot range should be at the least eighty–120% of the pattern. For sildenafil citrate the standard plot latitude was 0.8–1.2 mg and for impurities the range turned into 2–20 µg, which meets the ICH guidelines.
    outcomes
    a total of 15 sildenafil citrate pills were bought for pharmaceutical analysis: 14 commonplace samples from overseas information superhighway pharmacy websites and one pattern of the USA innovator product ().
    HPLC evaluation
    For sildenafil, an respectable assay components for content uniformity the use of HPLC has no longer been stated within the united states Pharmacopeia (USP), the British Pharmacopoeia (BP), or European Pharmacopoeia (EP). For the one hundred mg pill dosage variety of sildenafil, normal suited assay limits were posted in scientific journals. Daraghmeh and colleagues report an assay limit for sildenafil citrate of 98–102% and any person impurity should no longer exceed 0.5% of the MDD with complete impurity quantity not exceed 1% of the total each day dose [Daraghmeh et al. 2001]. besides the fact that children, most USP product monographs (as compared with substance monographs) have the common latitude for both manufactured products and compounded preparations as 90.0–a hundred and ten.0% [United States Pharmacopeial Convention, 2003; Allen, 2012].
    HPLC analysis indicated that 14 of the 15 drug samples had been within the standard USP latitude of ninety–a hundred and ten% of the labeled declare for each and every tablet dosage unit. youngsters, for the range of 98–102% of the labeled claim, best six of the drug samples were within this range ().
    evaluation of API amount in accumulated samples.
    the use of the linear regression formula, linear curves were plotted the usage of respective usual compounds for impurities A–D. HPLC analysis of the 15 samples gives variable records concerning the portions of impurities ().
    Impurity quantities (in micrograms) in sildenafil samples.
    in response to ICH guidelines, the qualification threshold for a dosage kind with a MDD of a hundred mg, reminiscent of sildenafil, is 200 µg. For impurity A, the entire samples were accompanied to be under the qualification threshold. The maximum impurity followed become 174.3 µg for pattern lot number SD237. For impurity B, four of the 15 samples confirmed greater than 200 µg, with 2 samples greater than 6 instances the qualification threshold. For impurity C, eight samples showed higher impurity limits than the qualification threshold. Impurity D was accompanied to be current in only in two samples in minute portions. among all samples, nine samples confirmed more than 0.5% of the MDD. In four samples, the entire impurity amount changed into more than the 1% of MDD. In sample #7 (Malegra, lot number E-134), the full impurity quantity turned into more than the 1.5% of MDD, and for pattern #11 (Integra lot quantity 1003003), the entire impurity quantity changed into greater than 2% of MDD.
    The innovator product contained distinctly low impurity portions. Impurities C and D had been under the limit of detection, and impurities A and B constituted under 37 µg, which is much beneath the qualification threshold.
    discussion
    A ‘cultural icon’ can be described as ‘an object that represents some element of the values, norms or beliefs perceived to be inherent in a tradition, or part of a culture’ [Wikipedia, 2014]. In ‘The Viagra Phenomenon’ Tiefer asserts ‘certain drug treatments, akin to aspirin, penicillin, contraception capsules, mood regulators (Valium and Prozac), and now Viagra, have develop into cultural icons, attaining a ways beyond just their have an impact on on human physiology to form social norms and practices’ [Tiefer, 2006]. truly, the American English observe ‘viaggravated’ is being adopted within the American lexicon, and is an adjective that ability ‘exhibiting a degree of sexual interest this is incongruent to one’s age’ [Merriam-Webster, 2014].
    youngsters nevertheless a multibillion dollar business, the marketplace for Viagra and different ‘virility’ medication has slowed in fresh years. In 2010, the whole variety of prescriptions for drugs used for erectile dysfunction fell by means of 5% after increase of simplest 1% yearly the previous four years. peculiarly, prescriptions for Viagra and Levitra declined 7% and 18%, respectively [James, 2011].
    This will also be contrasted with large boom of cyber web pharmacies, which have made prescription-best medication, akin to Viagra, quite simply obtainable online, and the increase and recognition doesn't seem like declining [Maxwell and Webb, 2008]. for instance, a search for ‘cyber web drug shop’ printed 6.4 million hits and of 7000 information superhighway pharmacies identified with the aid of the confirmed cyber web Pharmacy follow websites program (VIPPS) [Young, 2013]. of these websites that have been recognized, most effective 4% have been in proper compliance with regulations. What will be the impact on domestic income of Viagra? based on Lowe and Costabile, ‘The role information superhighway pharmacies play in counterfeit PDE5 or abuse isn't smartly documented; youngsters in keeping with handy entry, direct affected person advertising, and low advertised charge it is likely this position is underreported’ [Lowe and Costabile, 2011]. It isn't unreasonable to count on that illegal entry to Viagra by means of the web has had a terrible have an impact on on revenue of Viagra via regular healthcare channels.
    The documented hazards of taking Viagra include: counterfeit medication, probably harmful drug interactions, and accidental overdose, no longer to mention improper packaging and labeling () [Young, 2013; Webb et al. 1999; Hung and Yang, 2001; Veronin, 2011]. If one considers the expertise dangerous consequences of drug impurities, in all probability we now have brought to this listing of health hazards if a client chooses to buy sildenafil by means of the cyber web.
    universal sildenafil drugs obtained via the internet compared to the innovator product.
    in response to the U.S. Pharmacopeia, when it involves deciding upon the pleasant of a drug product, ‘realizing its impurity profile is as crucial as knowing concerning the fine of its active pharmaceutical ingredient (API) and excipients’ [The Standard, 2012]. what's the source of an impurity in a drug product? An impurity can be produced because of the drug’s manufacturing technique, or it can also be a degradation byproduct shaped when improper environmental situations exist, most likely during storage or transit. it could actually even be a substance deliberately brought throughout the manufacturing manner, reminiscent of a catalyst all over drug synthesis. in short, impurities are resources that may coexist in prescription drugs that serve no purpose for which the drug become designed [Rahman et al. 2006].
    In a previous analyze, four foremost impurities had been remoted within the oral dosage form of sildenafil citrate, and an HPLC formulation was developed and validated that might differentiate between the lively moiety and these impurities. The question then arises, if impurities don't have any useful position in a drug product, is there a chance that their existence may well be dangerous to an individual’s fitness or well-being?
    on the diverse tiers right through the drug manufacturing procedure, a whole lot of analytical exams are performed to make certain that the final drug product meets specifications for identity, electricity, pleasant, purity, and stability as designated in the u.s. Pharmacopeia and country wide Formulary (USP/NF). The USP/NF gives instructions for testing strategies and acceptance standards for these assessments [Chow et al. 2002].
    one of the most commonplace strategies for measuring API assay in oral dosage types is HPLC [Rudnic and Schwartz, 2000]. HPLC analysis can determine the efficiency of drugs, and hence security if drugs are discovered to be outdoor of the applicable first-class assurance range.
    For oral dosage varieties, when given that deviations from the label declare for efficiency, and degrees of impurities, a fair query can be, what are the brief- and long-time period health dangers?
    for the reason that there is no USP monograph for sildenafil pills, assay limits have been derived from standard assay guidelines for oral dosage types and research stories. for many business medicine manufactured in the US, the applicable efficiency latitude is ninety five–one hundred and five% or ninety–110% of the labeled quantity [Allen, 2012]. Of 14 samples analyzed from overseas markets, 6 of the items have been at or past the ±5% range, and 1 of the items changed into beyond the ±10% range and therefore would now not be applicable for sufferers in the US ().
    regarding levels of impurities, all samples registered detectable ranges of impurities. ranges of impurity A have been detectable in all samples, but none were above ICH qualification threshold. For impurity D, only 2 samples registered detectable quantities, and 13 of the 15 samples registered no detectable quantities. youngsters, for impurities B and C, for a couple of samples, the levels detected were above the ICH threshold, and the pills would no longer be applicable for sufferers within the US. For impurity B, 4 samples had been above both the ICH qualification threshold. The highest ranges of impurities have been evident for impurity C. Eight samples have been above each the ICH qualification threshold restrict. For samples above ICH limits for impurities B and C, they would now not handiest be unacceptable therapeutic agents for sufferers in the US, but additionally would be a trigger for alarm concerning health risks. These findings imply diverse manufacturing and/or storage approaches compared with the USA, which in flip may also affect quality, therapeutic effectiveness, and security. according to this advice, tests of protection for brief- and lengthy-time period use are warranted.
    barriers of the look at
    The noticeably small pattern dimension in this study MSC-131 may also not be an accurate representation of other sildenafil pills bought on the information superhighway and to generalize should be performed with a huge diploma of warning. however, the findings during this document support results with prior to now posted work [Westenberger et al. 2005; Veronin and Youan, 2004], and extra reports are warranted to identify developments in accessibility and health hazards for these styles of drug products bought on the information superhighway.
    When using analytical equipment, instrument and user error should be allowed for when on account that precision and accuracy of examine outcomes [Watson, 2005]. in this document, despite the fact each precaution turned into taken into consideration the opportunity exists that the values outside of suitable degrees may additionally or might also now not be as excessive as observed, if considering the margin of error of laboratory dimension.
    A intention of this analyze changed into to check nice attributes of efficiency and impurity ranges that can also in some way bring information on safeguard and effectiveness in the course of the dosage kind’s creation and/or storage properties. a right away affiliation between drug manufacturing attributes and scientific outcomes has now not been dependent, so the findings during this record must be interpreted with some reservation.
    Conclusions
    As this look at has shown, consumers can acquire prescription drugs by way of the web with little issue and without expert oversight. however general drug substitution is acceptable apply within the US, consumers deserve to be conscious that regardless of promoting claims on cyber web pharmacy web sites, patrons can also receive a drug product nonequivalent to the us counterpart and in contrast to what can be allowed for buyers within the US. additionally, it's fairly likely that the commonplace particular person searching for to import sildenafil from the information superhighway would obtain a product that does not meet great standards similar to the USA-made product. extra, it's nearly unimaginable to consider the nice of drugs bought from the information superhighway devoid of really good analytical testing. The outcomes of this examine point out variability of sildenafil offered on the information superhighway based on potency and impurity degrees, which may give pause to healthcare experts and buyers of these products.
    At a minimum, findings of this analyze suggest that sildenafil drugs bought from the web should not be considered interchangeable with the U.S. innovator product. These findings have implications for defense and effectiveness that should be considered by clinicians to doubtlessly protect sufferers who decide to purchase international-manufactured medication via the internet. past this, additional testing of the pharmacological results and drug interaction profiles of the impurities A, B, C, and D are warranted, to check the capabilities short- and long-term health dangers.
    Footnotes
    Funding: This research task turned into funded in part through the American heart affiliation Texas Affiliate #0565153Y.
    conflict of interest remark: The authors declare no battle of activity in making read MSC-131y this article.
    Contributor advice Michael A. Veronin, Texas A&M college fitness Science center Rangel college of Pharmacy - Pharmaceutical Sciences, MSC 131 1010 West Avenue B, Kingsville, TX 78363-8202, u . s ..
    Mohammad T. Nutan, Texas A&M institution health Science middle Rangel faculty of Pharmacy - Pharmaceutical Sciences, Kingsville, TX, u . s ..
    Uday Krishna Reddy Dodla, TechData carrier company, LLC - Statistical Programming, Morrisville, NC, u . s ..
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  • Webb D., Freestone S., Allen M., Muirhead G. (1999) Sildenafil citrate and blood-pressure-decreasing medication: results of drug interplay experiences with an biological nitrate and a calcium antagonist. Am J Cardiol 83(5A): 21C-28C [PubMed]
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    A gadget for de-choosing medical message board textual content
    so as to enrich and validate our gadget, we created a development set with 500 messages sampled from the BC corpus (31,232 non-punctuation tokens, 483 names complete) distinctive from the set on which our classifier turned into proficient, and a examine set with 500 messages sampled from the arthritis corpus (28,146 non-punctuation tokens, 432 names total). both of these sets were manually tagged via a human coder so as to evaluate the effectiveness of our equipment. Any token that referred to a user of the message board or any one that they had personal contact with changed into tagged as a name. This might also had been overly harsh because many of these tokens were acronyms or nicknames that have been unlikely to establish the consumer.
    although the majority of those sets were tagged by means of a single coder (AB), a subset of a hundred and twenty messages turned into also tagged through a different coder (AC) to produce an estimate of the only real coder’s reliability. Over this subset, AB tagged eighty three tokens as names and AC tagged eighty two as names; their tags agreed on eighty one tags (97.6% of tokens tagged as names through AB or ninety eight.9% tagged via AC).
    in an effort to increase our gadget, we experimented with a few distinct minimal name likelihood thresholds for tagging a token as a name and recorded the performance of our equipment the use of every of these thresholds over the development set. Fig.
    2
    suggests the precision-take into account curve because the likelihood threshold is distinct from 0.5 to 0.005. We then utilized the system to the arthritis test set which resulted in a precision of 61.four% and a do not forget of ninety four.three%.
    determine 2
    performance of our gadget over construction and examine sets, varying the likelihood threshold The blue curve shows the precision and bear in mind of our equipment over the development set, whereas various the probability threshold. during this figure, the values for the probability threshold ranged from 0.5 to 0.005 and are displayed for essential intervals on the curve. the edge price of 0.05 changed into chosen, given that it appeared to yield the highest recollect devoid of unnecessarily sacrificing precision over the building set. The red remoted aspect corresponds to the performance of our system, the usage of the chosen threshold value of 0.05, over the arthritis corpus examine set, while the blue point corresponds to its efficiency over the building set. The crimson curve corresponds to our equipment’s performance over the arthritis look at various set. word that this curve has an analogous trajectory to the efficiency over the BC construction set and that the factor of 0.05 probability threshold on it corresponds to an analogous precision/do not forget trade-off because the development curve.
    despite the fact the F-score decreases as the name probability threshold decreases, the don't forget raises dramatically with the aid of 15.5% (eighty two.6% to 98.1%) from the baseline of tagging tokens whose cumulative chance of being a name is improved than 50% to tagging any token whose cumulative probability exceeds 5%. For our project of de-identification, keep in mind is an awful lot more vital than precision, seeing that the simple intention is to maintain the authors' anonymity.
    observe that many tokens in the fashioned coding of the development and look at various units had been not going to give an awful lot information as to the identity of the creator. with the intention to precisely replicate our system’s capacity to eliminate choosing assistance, a second coding of those sets turned into carried out, the place any tokens that have been at first tagged as a reputation had been tagged as “different” if they were certainly one of: an acronym, a nickname that turned into surely unrelated to the author’s username or very own identify, or a substring of the username that become three or less characters long the place the username was over twice that length. Our device carried out a reputation don't forget of ninety nine.1% over the construction set and ninety five.four% over the look at various set after this recoding.
    The tokens where there changed into a discrepancy between the human coder and the device were categorized with the aid of category, as proven in Tables
    three
    and
    4
    . In desk
    3
    , “Ambig. commonplace words” refers to tokens that were most frequently nicknames for users, but now and then they have been proper names that had been misspelled as common ones (e.g., “lard” as a substitute of “lars”). “Prop. names” refers to tokens that were evidently proper names, spelled as it should be, besides the fact that children they may additionally not were in the gadget’s proper name listing. “Abbr./Acr.” were very short nicknames not than three characters and sometimes acronyms of usernames. “Misspelled usernames” have been usernames that had clearly been misspelled. These were decided to be misspelled usernames with the aid of relating to the creator names from the long-established thread MSC-131. “total N” refers to the complete variety of names that have been now not tagged as names through our gadget.
    desk 3
    Breakdown of the names that were no longer tagged as names via our device
    DEV
    50.0%
    20.0%
    30.0%
    0.0%
    10
    look at various
    48.1%
    7.four%
    33.three%
    11.1%
    27
    desk four
    Breakdown of the tokens that had been incorrectly tagged as names by using our equipment
    DEV
    35.three%
    13.5%
    6.three%
    forty four.9%
    207
    examine
    32.9%
    18.8%
    2.9%
    42.0%
    200
    In desk 4, “americans” refers to tokens that were names of genuine americans, however have been unrelated to any of the MMB authors (e.g., Oprah Winfrey, Tom Petty). “places/associations” refers to tokens relating to a location or organization. “clinical” tokens were tokens that stated a drug, supplement, method, or another medical thought and could be useful to researchers investigating these posts. “other” tokens couldn't be placed in any of the old four classes and would probably no longer be very helpful to researchers. Some examples of these are: “kiddo”, “june”, “april”, “morning”, “crispy”, and “sweetie”.
    with a purpose to examine our equipment’s efficiency in opposition t a at the moment obtainable de-identification equipment, we also ran the “Deid system” [9, 16] (http://www.physionet.org/physiotools/deid/) over our construction and examine units. The Deid equipment contains a single Perl script that depends on a mix of heuristics, typical expression, and notice lists to eliminate identifiers. We ran the equipment below a number of conditions. The equipment become run first devoid of altering any of its note lists, then via appending all the usernames on the message board to its checklist of ambiguous names, and eventually by way of appending all of those usernames to the listing of unambiguous names as a substitute. The system changed into first judged handiest on its skill to establish appropriate names after which on its capability to determine both suitable names and usernames. The device’s skill to establish usernames turned into bad in all cases (9.0%, 18.3%, and sixty seven.0% keep in mind for each of the three conditions respectively over the development set, and in a similar way over the test set) and the gadget’s precision under the ultimate condition was prohibitively low.
    We also evaluated the Stanford NER informed on a set of US and UK newswire over both these sets. table
    5
    simplest displays each methods’ means to determine relevant names on the grounds that neither the Deid gadget nor the Stanford NER have been designed to determine usernames, so it turned into unfair to evaluate their performance over these. Even including the entire set of author names to the Deid equipment’s unambiguous identify checklist resulted in a keep in mind of only sixty seven.0% of usernames and a drop to eleven.1% precision over the building set. The bad performance of these methods over our comparison units doesn't imply that they're dangerous at opting for names. It with ease highlights the incontrovertible fact that latest identify identification programs need to be developed for a selected area with the intention to perform neatly in it.
    desk 5
    performance of Deid device and Stanford named entity recognizer on construction and look at various units due to the fact only proper names
    DEV
    Precision
    fifty two.1%
    fifty one.2%
    11.1%
    61.7%
     
    remember
    86.3%
    84.2%
    86.three%
    81.2%
    verify
    Precision
    41.2%
    40.2%
    7.6%
    fifty five.4%
     
    recall
    eighty five.1%
    84.2%
    85.6%
    85.four%
    at last, we evaluated the performance of a freely purchasable state-of-the-artwork de-identification gadget, MIST (The MITRE Identification Scrubber Toolkit) [
    17
    ]. Like our gadget, MIST depends on a CRF to perform automatic tagging of identifiers, and finished the maximum general ranking within the de-identification project of the 2006 American medical Informatics association (AMIA) Challenges in herbal Language Processing for medical statistics [
    13
    ]. each of those information make MIST a superb gadget to consider our device against. We proficient MIST on the identical set of 1,000 breast melanoma MMB posts that our equipment become informed on and also blanketed the dictionaries listed in desk
    1
    as part of its lexicon. desk
    6
    reveals MIST’s efficiency over the BC and arthritis validation units towards the efficiency of our gadget.
    desk 6
    efficiency of state-of-the-artwork MIST de-identification system towards our equipment, over the construction and look at various sets
    MIST
    correct names
    79.9%
    80.5%
    seventy two.2%
    seventy four.9%
     
    Usernames
    49.5%
     
    34.3%
       
    All names
    seventy three.0%
     
    fifty four.6%
     
    Proposed device
    appropriate names
    ninety eight.9%
    67.four%
    ninety nine.0%
    sixty one.four%
     
    Usernames
    ninety four.5%
     
    90.three%
       
    All names
    98.1%
     
    ninety four.three%
     
    in this desk, don't forget is defined because the percentage of correct/user names that have been tagged with the aid of the gadget with some name tag (either a correct or a consumer name tag, the only viable identify tags) and precision turned into described as the share of non-name tokens that the device tagged with a name tag. We used this definition of consider and precision, because the removal of identifying suggestions is greater vital than the certain identify tags they're replaced with.

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(Choose all that apply.) install encode archive encrypt compress unencrypt Answer: B, C, E Question: 77 When you configure NFS export settings for a share point, selecting "Map All users to nobody" _. prevents export of any items or contents to any users tell the NFS server to treat every user the same: as nobody tells the NFS server to trust what the client reports for user identification creates a shared user list of valid IP addresses to communicate with via NFS Answer: B Question: 78 Using the Windows service in Server Admin, Mac OS X Server v10.3 can be configured to . (Choose all that apply.) allow Guest access reshare NFS volumes be an Active Directory server be a Primary Domain Controller be a member of a Windows workgroup Answer: A, D, E Question: 79 In Mac OS X Server v10.3, you should enable strict locking when you are sharing a volume over . FTP only AFP only SMB only AFT and FTP AFP and SMB Answer: E Question: 80 Network users often have multiple passwords, a distinct password for each network service they access. Which is NOT a valid way to simplify this situation for users in Mac OS X v10.3? Set up a Kerberos environment on the network. Have users store their login information for different servers in Keychain. Set up a directory service to make user and password information available to all computers. Have users access network servers without authenticating, using the Network icon in the Finder-rather than using the Connect Server command, which requires users to authenticate. Answer: D Question: 81 Which is an appropriate FIRST step when performing a software update on multiple computers That have Mac OS X v10.3? Restart each computer in single-user mode. On one computer, choose Download Checked items from the update menu in Software update. On one computer, choose copy update to multiple computers from the update menu in software update. Copy the Software Update preferences from a computer on which the update has been installed to all the other computers. Answer: B Question: 82 You are in a Terminal window, and your current directory is your home directory. What could you Type to display the contents of the file named my file? Which resides in your home directory? cat My File cat /Myfile cat~MyFile cat./MyFile cat ~/MyFile Answer: A, D, E Question: 83 Which statements are true about Open Directory? Choose all that apply Open Directory is extensible via plug-ins. Open Directory runs on Mac OS X Server only. Open Directory does NOT provide load balancing. You manage Open Directory using Open Directory Assisyant. An Open Directory server can function as a windows Primary Domain Controller. Answer: A, E Question: 84 What does the Console utility do? Displays log files Controls monitor setup. 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